Research Highlights

Bregman Iteration and Applications to Imaging and Sparse Representation

IPAM - January 2009

A breakthrough in the sparse representation of data was made in the Fall of 2004 by David Donoho and by Emmanuel Candes and Terence Tao, in part at IPAM’s Multiscale Geometry and Analysis program. Their important results reduce a computationally difficult problem to an easily stated, convex minimization problem (the basis pursuit problem): $$ \min |u|_1 \ \ \text{such that} \ \ Au = f.$$ In...

Modeling Placental Growth and Structure

IPAM - January 2009

Early life influences adult diseases. Such serious public health priorities as diabetes, heart disease, breast and prostate cancer, osteoporosis, and depression have all been related by recent medical studies to the development of the fetus. Environmental influences, such as maternal diseases, can cause irreversible metabolic consequences for the fetus, altering susceptibility to later adverse...

Voronoi Diagram of Ellipses

IMA - August 2008

Innumerable scientific and engineering applications from geology to telecommunications lead to the same problem: given a set of objects, find which object is nearest to any particular point. The Voronoi diagram answers this question for every point on the plane by dividing the plane into cells containing the points nearest each object. Because this question arises in so many applications,...

Shedding Light on Optics

IMA - August 2008

What you see is what you get… except when the thing you are looking at is either very small or very far away (all a matter of perspective). Take, for instance, the light from a street lamp projected through a hole the size of a fork tine in a screen. If you place another screen just behind the hole what you will see is an image of the hole. But as you move the second screen further and further...

Describing protein motions with nonlinear dimensionality reduction

IPAM - July 2008

Twenty years ago, commenting on macromolecular dynamics, Francis Crick wrote that “what seems to physicists a hopelessly complicated process may have been what Nature found simplest.” Indeed, if one uses molecular dynamics simulations (that follow the molecular motion of biological systems in the high dimensional Cartesian space spanned by each and all atomic degrees of freedom) the behavior of...

Therapeutic Use of Oxygen for Chronic Wounds

MBI - July 2008

Chronic wounds, like venous leg and diabetic foot ulcers (see right), are wounds that do not heal in a timely fashion, generally two-to-four weeks. Chronic wounds can cause pain and discomfort and also limit mobility. They are often a consequence of a more serious health problem, such as diabetes, heart disease, or blood circulation disorders. Left untreated, chronic wounds can lead to problems...

Math Dream

IAS - July 2008

New Connections of Representation Theory to Algebraic Geometry and Physics Representation theory is formally a branch of algebra which studies algebraic structure of symmetries. Its role in contemporary mathematics is due to the fact – realized through major discoveries of the 19th and 20th centuries mathematics – that the structure of symmetries holds key to understanding basic objects of...

Travel Time Tomography

IMA - June 2008

Inverse Problems are problems where causes for a desired or observed effect are to be determined. They arise in all fields of science and technology. An important example is to determine the density distribution inside a body from measuring the attenuation of X-rays sent through this body, the problem of “X-ray tomography.” Two types of inverse problems have intimate connections with a...

When The Volcano Blows

SAMSI - March 2008

“I don’t know where I’m gonna go when the volcano blows”. So wrote Jimmy Buffet. The more important challenge for volcanologists, however, is to determine “When should we go before the volcano blows!” Tackling this challenge was a principal focus of a group¹ of statisticians, mathematicians and volcanologists at SAMSI last year. The Soufriere Hills Volcano (right, April 2005) on the island of...

A New (Math) World

AIM - March 2008

A new mathematical object was revealed during a lecture at the American Institute of Mathematics (AIM). Two researchers from the University of Bristol exhibited the first example of a third degree transcendental L-function. These L-functions encode deep underlying connections between many different areas of mathematics. The news caused excitement at the AIM workshop attended by 25 of the...