For the past decade, the Institute’s Science Initiative Group (SIG) has worked with the World Bank and other partners to strengthen science in developing nations. In this talk, Phillip Griffiths, who helped create SIG when he was Director of the Institute from 1991 to 2003, will address the context for and evolution of SIG’s programs, with emphasis on the new Carnegie–IAS Regional Initiative in Science and Education (RISE), which prepares Ph.D.-level scientists and engineers in sub-Saharan Africa through university-based research and training networks.