Recently, algebraic methods have been developed to unify and advance a variety of techniques of statistical analysis, providing new and improved tools for computational biology. Professor Sturmfels, one of the founders of the new field of algebraic statistics, will introduce the subject and describe its emerging applications to genome science and developmental biology. He will be assisted by a fictional character named DiaNA who plays hopscotch and rolls tetrahedral dice with faces labeled "A," "C," "G," and "T."