In this talk, we present how signals and system theory was used for creating novel color solutions for digital production printing. We describe the system, mathematical formulation of the process, use of specialized algorithms, methods and architectures briefly, and then present focused research topics we are working on for transportation and healthcare systems. Integration of modern theories (e.g, compressed sensing, control & optimization theory), specialized optics with various imaging devices in the visible and infrared red wavelength bands will be presented aimed at creating next generation solutions and services business.