We introduce a novel aggregation framework to address multi-stage stochastic programs with mixed-integer state variables and continuous local variables (MSILPs). Our aggregation framework imposes additional structure to the integer state variables by leveraging the information of the underlying stochastic process, which is modeled as a Markov chain (MC). We present a novel branch-and-cut algorithm integrated with stochastic dual dynamic programming as an exact solution method to the aggregated MSILP, which can also be used in an approximation form to obtain dual bounds and implementable feasible solutions. Moreover, we apply two-stage linear decision rule (2SLDR) approximations and propose MC-based variants to obtain high-quality decision policies with significantly reduced computational effort. We test the proposed methodologies in a novel MSILP model for hurricane disaster relief logistics planning.