This talk will highlight the different pathways whereby climate mechanisms engender extreme events as well as harness that information to improve extreme event prediction. Since the beginning of the 21st century, a great deal of research effort has been undertaken toward uncovering the changing pattern of climate extremes. Aimed to be inclusive, this talk will review four parts of the climate extremes research: forcings, processes, regionality, and prediction. These four parts of climate science illuminate the progress toward developing actionable information to foresee the likelihood of a climate extreme, and so get ready for the event and its consequences.