Noah S. Diffenbaugh and Elizabeth A. Barnes Leveraging artificial neural networks (ANNs) trained on climate model output, we use the spatial pattern of historical temperature observations to predict the time until critical global warming thresholds are reached. Although no observations are used during the training, validation or testing, the ANNs accurately predict the timing of historical global warming from maps of historical annual temperature. The central estimate for the 1.5˚C global warming threshold is between 2033 and 2035, including a ±1 sigma range of 2028 to 2039 in the Intermediate (SSP2-4.5) climate forcing scenario, consistent with previous assessments. However, our data-driven approach also suggests substantial probability of exceeding the 2˚C threshold even in the Low (SSP1-2.6) climate forcing scenario. While there are limitations to our approach, our results suggest higher likelihood of reaching 2˚C in the Low scenario than indicated in previous assessments –– though the possibility that 2˚C could be avoided is not completely ruled out. Explainable AI (XAI) methods reveal that the ANNs focus on particular geographic regions to predict the time until the global threshold is reached. Our framework provides a unique, data-driven approach for quantifying the signal of climate change in historical observations, and for constraining the uncertainty in climate model projections. Given the substantial existing evidence of accelerating risks to natural and human systems at 1.5˚C and 2˚C, our results provide further evidence for high-impact climate change over the next three decades.