Massive data collection holds the promise of a better understanding of complex phenomena and ultimately, of better decisions. An exciting opportunity in this regard stems from the growing availability of perturbation / intervention data (manufacturing, advertisement, education, genomics, etc.). In order to obtain mechanistic insights from such data, a major challenge is the development of a framework that integrates observational and interventional data. I will present such a causal framework and discuss how it allows predicting the effect of yet unseen interventions and identifying the optimal interventions to perform.