Brian Van Essen - Lawrence Livermore National Laboratory In this talk we will present some of the recent work in the field and at LLNL to combine large scale deep learning with scientific simulations, notably a simulation on inertial confinement fusion. In addition to the challenges of training large models, we will present a simulation workflow that enables us to create sufficient training data set sizes, and how this work will come together in the future. We will also touch on several other success in applying large scale deep learning.