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Abstract

In this talk I discuss a number of examples of how bias can arise in scientific studies, emphasizing the importance of the role of blindness in evaluation as a key antidote to this basic problem. The double-blind, randomized controlled trial, in particular, has become the gold standard for scientific studies in clinical medicine; the reasons for the importance of each of the three elements in this approach will be laid out via a series of sobering and cautionary tales.

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